Recombinant Human GPNMB (C-6His)

Description

EnkiLife provides the Recombinant Human GPNMB (C-6His) protein,aslo know as Transmembrane Glycoprotein NMB,Transmembrane Glycoprotein HGFIN,GPNMB,HGFIN,NMB, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Glycoprotein Non-Metastatic Melanoma Protein B is produced by our Mammalian expression system and the target gene encoding Lys23-Pro486 is expressed with a 6His tag at the C-terminus.Accession:Q14956. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:53.09 KDa. Background:Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast, osteoblasts, myeloid dendritic cell, melanocytes, plus fetal chondrocytes and stratum basale keratinocytes, macrophages/keratinocytes.