Recombinant Human GSTP1

Description

EnkiLife provides the Recombinant Human GSTP1 protein,aslo know as Glutathione S-transferase P,GSTP1,GST class-pi,GSTP1-1,FAEES3,GST3, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Glutathione S-Transferase Pi 1 is produced by our E.coli expression system and the target gene encoding Met1-Gln210 is expressed.Accession:AAH10915.1. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:23.5 KDa. Background:Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.