Recombinant Human HAI-2 (C-6His)

Description

EnkiLife provides the Recombinant Human HAI-2 (C-6His) protein,aslo know as Kunitz-Type Protease Inhibitor 2,Hepatocyte Growth Factor Activator Inhibitor Type 2,HAI-2,Placental Bikunin,SPINT2,HAI2,KOP, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Hepatocyte Growth Factor Activator Inhibitor Type 2 is produced by our Mammalian expression system and the target gene encoding Ala28-Lys197 is expressed with a 6His tag at the C-terminus.Accession:O43291. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:20.22 KDa. Background:Hepatocyte Growth Factor Activator Inhibitor Type 2 (HAI2) is a single-pass type I membrane protein and contains two BPTI/Kunitz inhibitor domains. The first Kunitz domain is mainly responsible for the inhibitory activity against hepatocyte growth factor activator (HGFA). HAI2 is expressed in placenta, kidney, pancreas, prostate, testis, thymus and trachea. HAI2 serves as a inhibitor of HGF activator. It also inhibits plasmin, plasma and tissue kallikrein and factor XIa. Defects in HAI2 are the cause of diarrhea type 3 (DIAR3), also known as congenital sodium diarrhea (CSD).