Recombinant Human HMBS (C-6His)

Description

EnkiLife provides the Recombinant Human HMBS (C-6His) protein,aslo know as Porphobilinogen Deaminase,PBG-D,Hydroxymethylbilane Synthase,HMBS,Pre-Uroporphyrinogen Synthase,HMBS,PBGD,UPS, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Porphobilinogen Deaminase is produced by our Mammalian expression system and the target gene encoding Ser2-His361 is expressed with a 6His tag at the C-terminus.Accession:P08397. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:40.5 KDa. Background:Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the bodys organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.