Recombinant Human HYAL1 (C-6His)

Description

EnkiLife provides the Recombinant Human HYAL1 (C-6His) protein,aslo know as Hyaluronidase-1,Hyal-1,Hyaluronoglucosaminidase-1,Lung Carcinoma Protein 1,LuCa-1,HYAL1,LUCA1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Hyaluronidase-1 is produced by our Mammalian expression system and the target gene encoding Phe22-Trp435 is expressed with a 6His tag at the C-terminus.Accession:Q12794. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:47.18 KDa. Background:Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly expressed in the lung, placenta, and skeletal muscle. HYAL1 is thought to be involved in cell proliferation, migration, and differentiation. It may play a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.