Recombinant Human ICOSLG (C-6His)

Description

EnkiLife provides the Recombinant Human ICOSLG (C-6His) protein,aslo know as ICOS Ligand,B7 Homolog 2,B7-H2,B7-Like Protein Gl50,B7-Related Protein 1,B7RP-1,CD275,ICOSLG,B7H2,B7RP1,ICOSL,KIAA0653, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Inducible Co-Stimulator Ligand is produced by our Mammalian expression system and the target gene encoding Asp19-Ser258 is expressed with a 6His tag at the C-terminus.Accession:O75144. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:27.72 KDa. Background:Inducible Co-Stimulator Ligand (ICOSLG) belongs to the immunoglobulin superfamily. ICOSLG contains Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, it also induces B-cell proliferation and differentiation into plasma cells. It could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. ICOSLG is widely expressed lymph nodes, leukocytes and spleen, detected on activated monocytes and dendritic cells.