Recombinant Human IGF-I (67AA)

Description

EnkiLife provides the Recombinant Human IGF-I (67AA) protein,aslo know as Insulin-Like Growth Factor I,IGF-I,Mechano Growth Factor,MGF,Somatomedin-C,IGF1,IBP1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<0.5 EU/µg as determined by LAL test.;Construction:Recombinant Human Insulin-like Growth Factor I(4-70) is produced by our E.coli expression system and the target gene encoding Thr52-Ala118 is expressed.Accession:P05019. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:7.3 KDa. Background:Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.