Recombinant Human IGF2BP-2 (N-T7 ,C-6His)

Description

EnkiLife provides the Recombinant Human IGF2BP-2 (N-T7 ,C-6His) protein,aslo know as Insulin-Like Growth Factor 2 mRNA-Binding Protein 2,IGF2 mRNA-Binding Protein 2,IMP-2,Hepatocellular Carcinoma Autoantigen p62,IGF-II mRNA-Binding Protein 2,VICKZ Family Member 2,IGF2BP2,IMP2,VICKZ2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 is produced by our E.coli expression system and the target gene encoding Met1-Thr220 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.Accession:Q9Y6M1. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:27.2 KDa. Background:Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.