Recombinant Human IL-13 (C-mFc)

Description

EnkiLife provides the Recombinant Human IL-13 (C-mFc) protein,aslo know as Interleukin-13,IL-13, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Gly21/xadAsn132 is expressed with a mouse IgG1 Fc tag at the C-terminus.Accession:AAK53823. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:38.7 KDa. Background:Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.