Recombinant Human IL-15RA (C-Fc)

Description

EnkiLife provides the Recombinant Human IL-15RA (C-Fc) protein,aslo know as CD215,IL15RA,CD215 antigen,IL-15 receptor subunit alpha,IL-15RA,IL-15R-alpha,interleukin 15 receptor,alpha,interleukin-15 receptor subunit alpha,MGC104179, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Interleukin-15 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Ile31-Thr172 is expressed with a human IgG1 Fc tag at the C-terminus.Accession:Q13261-3. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:42.2 KDa. Background:Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.