Recombinant Human IL-17B (C-Fc)

Description

EnkiLife provides the Recombinant Human IL-17B (C-Fc) protein,aslo know as cytokine Zcyto7;IL-17B,interleukin-17 beta,interleukin-17B;neuronal interleukin-17 related factor,Neuronal interleukin-17-related factor,NIRF,ZCYTO7interleukin-Cytokine Zcyto7,cytokine-like protein ZCYTO7,interleukin-17 beta;interleukin-17B,interleukin 17B,neuronal interleukin-17 related factor,Neuronal interleukin-17-related factor;, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Interleukin-17B is produced by our Mammalian expression system and the target gene encoding Gln21-Phe180 is expressed with a human IgG1 Fc tag at the C-terminus.Accession:Q9UHF5. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:45.1 KDa. Background:Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases. In addition to IL-17B, members of the IL-17 family include IL-17A, IL-17C, IL-17D, IL-17E and IL-17F. The six IL-17 cytokines are highly conserved at C terminus, and contain five spatially conserved cysteine residues that mediate dimerization. Expression of IL-17B protein has been reported in neurons, testis, ovary, stomach, pancreas, small intestine and chondrocytes. IL-17B binds to Interleukine-17 receptor B (IL-17 RB) and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells.