Recombinant Human IL-18RAcP (C-6His)

Description

EnkiLife provides the Recombinant Human IL-18RAcP (C-6His) protein,aslo know as Interleukin-18 receptor accessory protein (IL18RAP),Accessory protein-like,CD218 antigen-like family member B,CDw218b,IL-1R accessory protein-like,Interleukin-1 receptor 7,Interleukin-18 receptor accessory protein-like,Interleukin-18 receptor beta£¨CD218b and IL1R7., which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Interleukin-18 Receptor Accessory Protein is produced by our Mammalian expression system and the target gene encoding Phe20-Arg356 is expressed with a 6His tag at the C-terminus.Accession:O95256. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:39.4 KDa. Background:IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.