Recombinant Human IL-1a

Description

EnkiLife provides the Recombinant Human IL-1a protein,aslo know as Interleukin-1 Alpha,IL-1 Alpha,Hematopoietin-1,IL1A,IL1F1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<0.01 EU/µg as determined by LAL test.;Construction:Recombinant Human Interleukin-1 Alpha is produced by our E.coli expression system and the target gene encoding Ser113-Ala271 is expressed.Accession:P01583. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:18 KDa. Background:Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.