Recombinant Human IL-1RAPL1 (C-6His)

Description

EnkiLife provides the Recombinant Human IL-1RAPL1 (C-6His) protein,aslo know as Interleukin-1 Receptor Accessory Protein-Like 1,IL-1-RAPL-1,IL-1RAPL-1,IL1RAPL-1,Oligophrenin-4,Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2,TIGIRR-2,X-Linked Interleukin-1 Receptor Accessory Protein-Like 1,IL1RAPL1,OPHN4, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Interleukin-1 Receptor Accessory Protein-like 1 is produced by our Mammalian expression system and the target gene encoding Leu19-Val360 is expressed with a 6His tag at the C-terminus.Accession:Q9NZN1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:40 KDa. Background:Interleukin-1 receptor accessory protein-like 1, also known as IL1RAPL1, can be detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. IL1RAPL1 functions as a homodimer, it interacts with NCS1, PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation, it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.