Recombinant Human IL-20RB (C-Fc)

Description

EnkiLife provides the Recombinant Human IL-20RB (C-Fc) protein,aslo know as Interleukin-20 receptor subunit beta,IL-20 receptor subunit beta,IL-20R-beta,IL-20RB,IL-20R2,DIRS1,hCG_2022374,FNDC6,MGC34923, fibronectin type III domain containing 6,interleukin-20 receptor II, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Interleukin-20 Receptor Subunit Beta/IL-20RB is produced by our Mammalian expression system and the target gene encoding Asp30-Ala230 is expressed with a human IgG1 Fc tag at the C-terminus.Accession:Q6UXL0. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:49.6 KDa. Background:Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family.