Recombinant Human IL-23

Description

EnkiLife provides the Recombinant Human IL-23 protein,aslo know as SGRF, IL-23p19, CLMF p40, IL-12 subunit p40, NKSF2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:≤10 EU/mg;Construction:Recombinant Human IL-23 is produced by our Mammalian cell expression system and the target gene encoding Ile23-Ser328&Arg23-Pro189 is expressed.Accession:P29460(P40), AAG37232(P19). Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:55.0 kDa(IL-23singlechain);36.5 kDa(p40)&18.5 kDa(p19). Background:Interleukin-23 (IL-23) is a heterodimeric cytokine that belongs to the IL-12 cytokine family. It is composed of two subunits, p19 and p40, with the p40 subunit being shared with IL-12. IL-23 is primarily secreted by activated macrophages and dendritic cells located in peripheral tissues such as skin, intestinal mucosa, and lung. This cytokine plays a crucial role in the development and maintenance of autoimmune inflammation, particularly through its ability to induce IL-17 production, which is a unique role compared to IL-12.