Recombinant Human IL-4 (E. coli)

Description

EnkiLife provides the Recombinant Human IL-4 (E. coli) protein,aslo know as Interleukin-4,IL-4,B-Cell Stimulatory Factor 1,BSF-1,Binetrakin,Lymphocyte Stimulatory Factor 1,Pitrakinra,IL4, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<0.01 EU/µg as determined by LAL test.;Construction:Recombinant Human Interleukin-4 is produced by our E.coli expression system and the target gene encoding His25-Ser153 is expressed.Accession:P05112. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:15.1 KDa. Background:Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.