Recombinant Human IL18R1 (C-6His)

Description

EnkiLife provides the Recombinant Human IL18R1 (C-6His) protein,aslo know as Interleukin-18 receptor 1,IL18R1,CD218 antigen-like family member A,CDw218a,IL1 receptor-related protein,IL-1Rrp,Interleukin-18 receptor alpha,IL-18R-alpha,CD218a,IL1RRP, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Interleukin-18 Receptor 1 is produced by our Mammalian expression system and the target gene encoding Ala19-Arg329 is expressed with a 6His tag at the C-terminus.Accession:Q13478. Expression Host:Human cells.Species:Human.Predicted Molecular Mass:36.6 KDa. Background:The interleukin 18 receptor 1 (IL18R1) belongs to interleukin 1 receptor family. IL18R1 is of particular interest since the receptor is critical for experimental neuroinflammation. Reaserches show that the increased expression of IL18R1 may contribute pathogenically to disease and is therefore a potential therapeutic target. IL18R1 has been shown to mediate EAE through regulation of both IL-18-dependent and –independent pathways.