Recombinant Human INPP5A (C-6His)

Description

EnkiLife provides the Recombinant Human INPP5A (C-6His) protein,aslo know as Type I inositol 1;4;5-trisphosphate 5-phosphatase,INPP5A, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Type I Inositol-polyphosphate Phosphatase is produced by our Mammalian expression system and the target gene encoding Met1-Val410 is expressed with a 6His tag at the C-terminus.Accession:Q14642. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:48.7 KDa. Background:Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.