Recombinant Human KPNA2 (N-6His)

Description

EnkiLife provides the Recombinant Human KPNA2 (N-6His) protein,aslo know as Importin Subunit Alpha-2,Karyopherin Subunit Alpha-2,RAG Cohort Protein 1,SRP1-Alpha,KPNA2,RCH1,SRP1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Karyopherin Subunit Alpha-2 is produced by our E.coli expression system and the target gene encoding Met1-Phe529 is expressed with a 6His tag at the N-terminus.Accession:P52292. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:60.04 KDa. Background:Karyopherin Subunit α-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1.