Recombinant Human LDH-B (N-6His)

Description

EnkiLife provides the Recombinant Human LDH-B (N-6His) protein,aslo know as L-lactate Dehydrogenase B Chain,LDH-B,LDH Heart Subunit,LDH-H,Renal Carcinoma Antigen NY-REN-46,LDHB, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human L-Lactate Dehydrogenase B Chain is produced by our E.coli expression system and the target gene encoding Met1-Leu334 is expressed with a 6His tag at the N-terminus.Accession:P07195. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:38.8 KDa. Background:L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C; members of this family function as powerful markers for germ cell tumors. LDH-B is an oxidoreductase that catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. It converts pyruvate to lactate when oxygen is absent or in short supply and it performs the reverse reaction during the Cori cycle in the liver. It is also called Hydroxybutyrate Dehydrogenase (HBD) due to its ability to catalyze the oxidation of hydroxybutyrate.