Recombinant Human LGALS3 (C-6His)

Description

EnkiLife provides the Recombinant Human LGALS3 (C-6His) protein,aslo know as Galectin-3,Gal-3,35 kDa Lectin,Carbohydrate-Binding Protein 35,CBP 35,Galactose-Specific Lectin 3,Galactoside-Binding Protein,GALBP,IgE-Binding Protein,L-31,Laminin-Binding Protein,Lectin L-29,Mac-2 Antigen,LGALS3,MAC2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Galectin-3 is produced by our Mammalian expression system and the target gene encoding Ala2-Ile250 is expressed with a 6His tag at the C-terminus.Accession:AAH53667.1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:27.2 KDa. Background:Galectin-3(LGALS3) is also known as Galactose-specific lectin 3, Mac-2 antigen, Carbohydrate-binding protein 35, Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma, and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic properties. LGLAS3 takes part in an immune regulator to inhibit T-cell immune responses and promote tumor growth, as a result providing a new mechanism for tumor immune tolerance.