Recombinant Human LSM1 (C-6His)

Description

EnkiLife provides the Recombinant Human LSM1 (C-6His) protein,aslo know as U6 snRNA-Associated Sm-Like Protein LSm1,Cancer-Associated Sm-Like,Small Nuclear Ribonuclear CaSm,LSM1,CASM, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1 is produced by our E.coli expression system and the target gene encoding Met1-Tyr133 is expressed with a 6His tag at the C-terminus.Accession:O15116. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:16.23 KDa. Background:U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.