Recombinant Human LTA4H (C-6His)

Description

EnkiLife provides the Recombinant Human LTA4H (C-6His) protein,aslo know as Leukotriene A-4 hydrolase;LTA-4 hydrolase;Leukotriene A(4) hydrolase,LTA4;LTA4H, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Leukotriene A-4 Hydrolase is produced by our Mammalian expression system and the target gene encoding Met1-Asp611 is expressed with a 6His tag at the C-terminus.Accession:P09960. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:70.3 KDa. Background:LTA4H, which is short for Leukotriene A-4 hydrolase, is a 611 aa. protein. It belongs to the peptidase M1 family, and exists in cytoplasm. This protein has at least 4 isforms produced by alternative splicing, and two of them are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. LTA4H involves in lipid metabolism and leukotriene B4 biosynthesis. It is a epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. It also has aminopeptidase activity