Recombinant Human LYVE-1 (C-6His)

Description

EnkiLife provides the Recombinant Human LYVE-1 (C-6His) protein,aslo know as Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1,LYVE-1,Cell Surface Retention Sequence-Binding Protein 1,CRSBP-1,Extracellular Link Domain-Containing Protein 1,Hyaluronic Acid Receptor,LYVE1,CRSBP1,HAR,XLKD1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is produced by our Mammalian expression system and the target gene encoding Leu20-Thr238 is expressed with a 6His tag at the C-terminus.Accession:AAH26231.1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:24.6 KDa. Background:Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.