Recombinant Human MINPP1 (C-6His)

Description

EnkiLife provides the Recombinant Human MINPP1 (C-6His) protein,aslo know as Multiple Inositol Polyphosphate Phosphatase 1,2;3-Bisphosphoglycerate 3-Phosphatase,2;3-BPG Phosphatase,Inositol (1;3;4;5)-Tetrakisphosphate 3-Phosphatase,Ins(1;3;4;5)P(4) 3-Phosphatase,MINPP1,MIPP, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Leu487 is expressed with a 6His tag at the C-terminus.Accession:Q9UNW1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:53.14 KDa. Background:Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).