Recombinant Human MOG (C-6His)

Description

EnkiLife provides the Recombinant Human MOG (C-6His) protein,aslo know as Myelin-Oligodendrocyte Glycoprotein,MOG,MOG(1-125), which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Myelin Oligodendrocyte Glycoprotein is produced by our Mammalian expression system and the target gene encoding Gly30-Gly154 is expressed with a 6His tag at the C-terminus.Accession:Q16653. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:15.31 KDa. Background:Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space which allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like disease in experimental animals,namely experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys.