Recombinant Human MPZL1 (C-6His)

Description

EnkiLife provides the Recombinant Human MPZL1 (C-6His) protein,aslo know as Myelin protein zero-like 1,isoform CRA_b;cDNA FLJ78597,highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1),transcript variant 1,mRNA ;cDNA,FLJ96614,Homo sapiens myelin protein zero-like 1 (MPZL1),Mrna, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Myelin Protein P0-like 1 is produced by our Mammalian expression system and the target gene encoding Ser36-Val162 is expressed with a 6His tag at the C-terminus.Accession:O95297. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:15.2 KDa. Background:Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.