Recombinant Human/Murine/Rat BDNF

Description

EnkiLife provides the Recombinant Human/Murine/Rat BDNF protein,aslo know as Brain-Derived Neurotrophic Factor,BDNF,Abrineurin, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<0.01 EU/µg as determined by LAL test.;Construction:Recombinant Human Brain-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed.Accession:P23560. Expression Host:E.coli.Species:Human/Mouse/Rat.Predicted Molecular Mass:13 KDa. Background:Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinsons and Alzheimers disease.