Recombinant Human NDPKA (N-6His)

Description

EnkiLife provides the Recombinant Human NDPKA (N-6His) protein,aslo know as Nucleoside Diphosphate Kinase A,NDK A,NDP Kinase A,Granzyme A-Activated DNase,GAAD,Metastasis Inhibition Factor nm23,Tumor Metastatic Process-Associated Protein,nm23-H1,NME1,NDPKA,NM23, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Nucleoside Diphosphate Kinase A is produced by our E.coli expression system and the target gene encoding Met1-Glu152 is expressed with a 6His tag at the N-terminus.Accession:P15531. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:19.3 KDa. Background:Nucleoside-Diphosphate Kinases (NDKs) are enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. NDKs Possesse nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3-5 exonuclease activities. NDKs involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression and required for neural development including neural patterning and cell fate determination. Prokaryotic NDK forms a functional homotetramer.There are two isoforms of NDK in humans: NDK-A and NDK-B. Both have very similar structure, and can combine in any proportion to form functional NDK hexamers.