Recombinant Human NHP2L1 (N-6His)

Description

EnkiLife provides the Recombinant Human NHP2L1 (N-6His) protein,aslo know as NHP2-Like Protein 1,High Mobility Group-Like Nuclear Protein 2 Homolog 1,OTK27,SNU13 Homolog,hSNU13,U4/U6.U5 tri-snRNP 15.5 kDa Protein,NHP2L1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human NHP2-Like Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Val128 is expressed with a 6His tag at the N-terminus.Accession:P55769. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:16.3 KDa. Background:NHP2-Like Protein 1 (NHP2L1) is a member of the ribosomal protein L7Ae family. NHP2L1 proteinis limited to the nucleus, primarily focused in the dense fibrillar component of the nucleolus. NHP2L1 has been shown to interact with RAD17and PRPF31. The protein undergoes a conformational change upon RNA-binding. NHP2L1 binds to the 5-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly, prior to step I of splicing catalysis.