Recombinant Human NLGN1 (C-6His)

Description

EnkiLife provides the Recombinant Human NLGN1 (C-6His) protein,aslo know as Neuroligin-1,NLGN1,KIAA1070, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Neuroligin 1 is produced by our Mammalian expression system and the target gene encoding Gln46-Leu676 is expressed with a 6His tag at the C-terminus.Accession:Q8N2Q7-2. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:71.5 KDa. Background:Neuroligin-1 is a single-pass type I transmembrane protein which belongs to the type-B Carboxylesterase/Lipase family. Neuroligins are cell-adhesion molecules located at the postsynaptic side of the synapse. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. Neurexins and Neuroligins are cell adhesion molecules present in excitatory and inhibitory synapses, and they are required for correct neuron network function. These proteins are found at the presynaptic and postsynaptic membranes. Neuroligin-1 is a neuronal cell surface protein which is thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. It seems to play role in formation or maintenance of synaptic junctions. It triggers the de novo formation of presynaptic structures and may be involved in specification of excitatory synapses.