Recombinant Human Otolin-1 (C-6His)

Description

EnkiLife provides the Recombinant Human Otolin-1 (C-6His) protein,aslo know as OTOL1,otolin 1,Otolin-1,C1qTNF15, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Otolin-1 is produced by our Mammalian expression system and the target gene encoding Lys24-Pro477 is expressed with a 6His tag at the C-terminus.Accession:A6NHN0. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:47.7 KDa. Background:Otolin (OTOL1), also known as C1qTNF15, is an approximately 65 kDa protein found in the otoconial membrane lining the cochlea and vestibular labyrinth of the inner ear. Collagen-like protein specifically expressed in the inner ear, which provides an organic scaffold for otoconia, a calcium carbonate structure in the saccule and utricle of the ear. It associates into multimers and disulfide-linked oligomers and also associates with other otoconial proteins including and Otoconin-90 (also known as PLA2G2A, PLA2L, and phospholipase A2 homolog) and Cerebellin-1. It is extensively glycosylated and has multiple hydroxylated proline residues in the collagenous regions.