Recombinant Human P4HB (C-6His)

Description

EnkiLife provides the Recombinant Human P4HB (C-6His) protein,aslo know as Protein Disulfide-Isomerase,PDI,Cellular Thyroid Hormone-Binding Protein,Prolyl 4-Hydroxylase Subunit Beta,p55,P4HB,ERBA2L,PDI,PDIA1,PO4DB, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Prolyl 4-Hydroxylase Subunit Beta is produced by our Mammalian expression system and the target gene encoding Asp18-Lys505 is expressed with a 6His tag at the C-terminus.Accession:P07237. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:55.9 KDa. Background:Protein Disulfide-Isomerase (P4HB) is an endoplasmic reticulum lumen protein that belongs to the protein disulfide isomerase family. P4HB contains two thioredoxin domains and catalyzes the formation, breakage, and rearrangement of -S-S- bonds in proteins. P4HB is involved in hydroxylation of prolyl residues in preprocollagen. P4HB has the ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner. P4HB plays a role in both the influx and efflux of S-nitrosothiol-bound nitric oxide.