Recombinant Human PAP (N-6His)

Description

EnkiLife provides the Recombinant Human PAP (N-6His) protein,aslo know as 28 kDa Heat- and Acid-Stable Phosphoprotein,PDGF-Associated Protein,PAP,PDGFA-Associated Protein 1,PAP1,PDAP1,HASPP28, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human PDGF-Associated Protein is produced by our E.coli expression system and the target gene encoding Met1-Lys181 is expressed with a 6His tag at the N-terminus.Accession:Q13442. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:22.79 KDa. Background:Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.