Recombinant Human PD-L2 (C-mFc)

Description

EnkiLife provides the Recombinant Human PD-L2 (C-mFc) protein,aslo know as Programmed Cell Death 1 Ligand 2,PD-1 Ligand 2,PD-L2,PDCD1 Ligand 2,Programmed Death Ligand 2,Butyrophilin B7-DC,B7-DC,CD273,PDCD1LG2,B7DC,CD273,PDCD1L2,PDL2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Programmed Cell Death 1 Ligand 2 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro219 is expressed with a mouse IgG1 Fc tag at the C-terminus.Accession:Q9BQ51. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:49.2 KDa. Background:Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.