Recombinant Human Periostin (C-6His)

Description

EnkiLife provides the Recombinant Human Periostin (C-6His) protein,aslo know as Osteoblast-specific factor 2,OSF-2,POSTN,Periostin, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Osteoblast Specific Factor 2 is produced by our Mammalian expression system and the target gene encoding Asn22-Gln779 is expressed with a 6His tag at the C-terminus.Accession:Q15063-2. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:85.6 KDa. Background:Osteoblast-Specific Factor OSF-2 (POSTN, Periostin, OSF-2) is a secreted, homodimeric protein that belongs to the periostin family of the FAS1 superfamily of molecules. Periostin is a disulfide linked 90kDa bone adhesion protein secreted by osteoblasts and osteoblast-like cell lines and the protein is an attachment agent for osteoblasts. It is a TGF-beta inducible molecule that serves as both an adhesion molecule and tumor suppressor. It is synthesized by smooth muscle cells, fibroblasts and osteoblasts, as well as in the periosteum and periodontal ligament. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells.