Recombinant Human PFKFB1 (C-6His)

Description

EnkiLife provides the Recombinant Human PFKFB1 (C-6His) protein,aslo know as 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1,6PF-2-K/Fru-2,6-P2ase liver isozyme,Fructose-2,6-bisphosphatase,PFKFB1,F6PK,PFRX, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser2-Tyr471 is expressed with a 6His tag at the C-terminus.Accession:P16118. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:55.6 KDa. Background:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.