Recombinant Human PGDS

Description

EnkiLife provides the Recombinant Human PGDS protein,aslo know as Hematopoietic Prostaglandin D Synthase,H-PGDS,GST Class-Sigma,Glutathione S-Transferase,Glutathione-Dependent PGD Synthase,Glutathione-Requiring Prostaglandin D Synthase,Prostaglandin-H2 D-Isomerase,HPGDS,GSTS,PGDS,PTGDS2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Hematopoietic Prostaglandin D Synthase is produced by our E.coli expression system and the target gene encoding Met1-Leu199 is expressed.Accession:O60760. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:22.3 KDa. Background:Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.