Recombinant Human PPIH (N-6His)

Description

EnkiLife provides the Recombinant Human PPIH (N-6His) protein,aslo know as Peptidyl-Prolyl Cis-Trans Isomerase H,PPIase H,Rotamase H,Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H,CypH,U-snRNP-Associated Cyclophilin SnuCyp-20,USA-CYP,PPIH,CYP20,CYPH, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase H is produced by our E.coli expression system and the target gene encoding Met1-Met177 is expressed with a 6His tag at the N-terminus.Accession:O43447. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:21.4 KDa. Background:Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.