Recombinant Human PRAP1 (C-6His)

Description

EnkiLife provides the Recombinant Human PRAP1 (C-6His) protein,aslo know as Proline-Rich Acidic Protein 1,Epididymis Tissue Protein Li 178,Uterine-Specific Proline-Rich Acidic Protein,PRAP1,UPA, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Proline-Rich Acidic Protein 1 is produced by our Mammalian expression system and the target gene encoding Val21-Gln151 is expressed with a 6His tag at the C-terminus.Accession:AAL16670.1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:16.04 KDa. Background:Proline-rich acidic protein 1, also known as Uterine-specific proline-rich acidic protein, UPA and PRAP1, is a secreted protein. PRAP1 is abundantly expressed in the epithelial cells of the liver, kidney, gastrointestinal tract and cervix. PRAP1 is up-regulated by butyrate, trichostatin A and 5-aza-2 deoxycytidine. PRAP1 may play an important role in maintaining normal growth homeostasis in epithelial cells. PRAP1 is suppressed through epigenetic mechanisms involving histone deacetylation and methylation. PRAP1 has been shown to cause cell growth inhibition in cancer cell lines.