Recombinant Human PRCP (C-6His)

Description

EnkiLife provides the Recombinant Human PRCP (C-6His) protein,aslo know as Lysosomal Pro-X Carboxypeptidase,Angiotensinase C,Lysosomal Carboxypeptidase C,Proline Carboxypeptidase,Prolylcarboxypeptidase,PRCP,PRCP,PCP, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Lysosomal Pro-X Carboxypeptidase is produced by our Mammalian expression system and the target gene encoding Leu22-His496 is expressed with a 6His tag at the C-terminus.Accession:P42785. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:54.5 KDa. Background:Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.