Recombinant Human PRDX4 (N-6His)

Description

EnkiLife provides the Recombinant Human PRDX4 (N-6His) protein,aslo know as Peroxiredoxin-4,Antioxidant Enzyme AOE372,AOE37-2,Peroxiredoxin IV,Prx-IV,Thioredoxin Peroxidase AO372,Thioredoxin-Dependent Peroxide Reductase A0372,PRDX4, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Peroxiredoxin-4 is produced by our E.coli expression system and the target gene encoding Trp38-Asn271 is expressed with a 6His tag at the N-terminus.Accession:Q13162. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:28.9 KDa. Background:Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.