Recombinant Human pro-Beta NGF

Description

EnkiLife provides the Recombinant Human pro-Beta NGF protein,aslo know as Beta-Nerve Growth Factor,Beta-NGF,NGF,NGFB;β-NGF,pro-Beta NGF, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human pro-Nerve Growth Factor is produced by our E.coli expression system and the target gene encoding Glu19-Ala241 is expressed.Accession:P01138. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:25 KDa. Background:The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.