Recombinant Human PSP (C-6His)

Description

EnkiLife provides the Recombinant Human PSP (C-6His) protein,aslo know as Phosphoserine Phosphatase,PSP,PSPase,L-3-Phosphoserine Phosphatase,O-Phosphoserine Phosphohydrolase,PSPH, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Phosphoserine Phosphatase is produced by our E.coli expression system and the target gene encoding Met1-Glu225 is expressed with a 6His tag at the C-terminus.Accession:P78330. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:26.07 KDa. Background:Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.