Recombinant Human RANK (C-6His)

Description

EnkiLife provides the Recombinant Human RANK (C-6His) protein,aslo know as CD265,ODFR,TNFRSF11A,TRANCE R,CD265,CD265 antigen,FEO,ODFROSTS,OFE,OPTB7, PDB2,RANK1,Receptor activator of NF-KB,receptor activator of nuclear factor-kappa B,TRANCER,tumor necrosis factor receptor superfamily member 11A, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Receptor Activator of NF-kappa-B is produced by our Mammalian expression system and the target gene encoding Ile30-Pro212 is expressed with a 6His tag at the C-terminus.Accession:Q9Y6Q6. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:21.1 KDa. Background:Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.