Recombinant Human RNASE3 (C-6His)

Description

EnkiLife provides the Recombinant Human RNASE3 (C-6His) protein,aslo know as Eosinophil Cationic Protein,ECP,Ribonuclease 3,RNase 3,RNASE3,ECP,RNS3, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Ribonuclease 3 is produced by our Mammalian expression system and the target gene encoding Arg28-Ile160 is expressed with a 6His tag at the C-terminus.Accession:AAH96060.1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:16.6 KDa. Background:Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.