Recombinant Human SENP7

Description

EnkiLife provides the Recombinant Human SENP7 protein,aslo know as Sentrin-Specific Protease 7,SUMO-1-Specific Protease 2,Sentrin/SUMO-Specific Protease SENP7,SENP7,KIAA1707,SSP2,SUSP2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Sentrin-Specific Protease 7 is produced by our E.coli expression system and the target gene encoding Met695-Ala864 is expressed.Accession:Q9BQF6. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:19.8 KDa. Background:Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.