Recombinant Human Serpin A3 (C-6His)

Description

EnkiLife provides the Recombinant Human Serpin A3 (C-6His) protein,aslo know as Alpha-1-Antichymotrypsin,ACT,Cell Growth-Inhibiting Gene 24/25 Protein,Serpin A3,SERPINA3,AACT, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Serine Protease Inhibitor-clade A3 is produced by our Mammalian expression system and the target gene encoding His24-Ala423(Lys267Arg) is expressed with a 6His tag at the C-terminus.Accession:P01011. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:46.33 KDa. Background:Serpin A3 belongs to the Serpin superfamily of serine protease inhibitors. Serpin A3 has been shown to inhibit some serine proteases, such as neutrophil cathepsin G and mast cell chymase. Serpin A3 is synthesized initially in the liver and secreted in plasma. Serpin A3 has been found in the amyloid plaques from the hippocampus of Alzheimer disease brains. In addition to, Serpin A3 is associated with liver disease and Parkinson disease and chronic obstructive pulmonary disease.