Recombinant Human Serpin A4 (C-6His)

Description

EnkiLife provides the Recombinant Human Serpin A4 (C-6His) protein,aslo know as Kallistatin,Kallikrein Inhibitor,Peptidase Inhibitor 4,PI-4,Serpin A4,SERPINA4,KST,PI4, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Serine Protease Inhibitor-clade A4 is produced by our Mammalian expression system and the target gene encoding Gln21-Pro427 is expressed with a 6His tag at the C-terminus.Accession:P29622. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:47.1 KDa. Background:Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition, Serpin A4 has anti-inflammatory effect. Heparin blocks kallistatins complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikreins activity.